Good start

Logging a pill taken is easy, 1-2 clicks... except: if you take a pill at bedtime, and bedtime is past midnight, you simply cant mark the pill taken.
Speech integration, or at least a custom/distinct alarm would help provide a reminder when youre in the area, but not directly at the computer.
Adding pill information is simple and fast since there are only, at most three boxes to fill out (time, frequency, and, if you like, a description). The most frequent dosage option is daily, but you can just add in the pm dose, for example, as another pill.
It would be nice to be able to change how many days show up in the pillbox, especially since you cant log previous/future doses anyway.
The addition of supply logging would be great for metered dose inhalers, where the patient has to count down from 200 to know how many doses are left, that, however, would require granularities more frequent than daily.
Its a bit limited at this stage, but its so easy to use and so inexpensive.

Sadly, Ive had to stop using it because of memory leaks since one of the later version 1 updates. The concept is great. The feature set with version 2 is terrific, but it can quickly hog 1 GB of memory and halt my computer. Ive not yet upgraded to Snow Leopard.

respirar about Pill Reminder